Would die for a Still Life mixed with Syberia mixed with Book of Unwritten Tales.
(Just realized this should of been mentioned in the Adventure Game theme thread too.)
Syberia has a VERY unique feel to it. From the gray, depressing atmosphere to the architectural design familiar to the developer's homeland and culture. They chose not to make anything that all that looked reminisent of our own lifestyle. Even the village buildings looked unique. Thats probably why we haven't had a game that satisfied our thirsts like Syberia did.
Syberia felt fantastical without going to far out of the way of being complete fantasy. It felt a little romantic in terms of our connection with the world.