Personally, I dislike both McAfee and especially Norton. AVG used to be good, but over the past year or two, I have had several people bring me their PCs because they had become too slow to be usable. The culprit in most cases proved to be AVG, even after a fresh clean install of Windows.
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Microsoft Security Essentials has been getting great reviews, even by security expert Steve Gibson, the author of the very first anti spyware program. It is free and has far fewer false positives than most antivirus programs. Though the scanning is somewhat slower, it is more through.
