In random order of awesomeness:
Mass Effect
Stranglehold
HL2 episodes
Hitman: Blood Money
Spore
SC4: Double Agent
BioShock
Battlefield 2142 (perhaps, I've bought every BF game, but I'm very very sceptical about this 'futuristic' one)
Huxley (as long as there are no monthly fees)
-wotsitsname- that pirate game that looks awesome
Okami (even though I don't have a PS2)
Africa
Crysis (
)
KOTOR 3 (it'll happen someday
)
The Stalin Subway (perhaps)
Chromehounds
Tomb Raider Legends
"Sam & Max 2" (who knows)
The Longest Journey 3/Dreamfall 2
Broken Sword 4
Paradise
Monkey Island 5
No One Lives Forever 3
Deus Ex 3
Sure I forgot loads, but that's all I can think of at the moment.