I read all kinds of Ultimate series from Marvel: Fantastic Four, Spiderman, X-Men, the Ultimates (the Ultimate universe version of the Avengers), and they're all pretty cool. The one gripe I have with the new F4 movie is that they didn't make Victor's transformation as cool or as scary as it was in the Ultimate comics (that aint no face mask! It's his face! And he's got disjointed legs! And spikes! And poison gas!).
As for the more...ahem...sophisticated stuff:
Invincible
Walking Dead
Fables
Y the last man. All excellent.
BTW, I read We3, it was awesome!