The answers below are my opinions, others may disagree.
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Originally Posted by tsa
[*]Who was the first girl who wanted to apply for the assistant job?
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Someone from the biology department (or whatever dept it is that David and Mrs. Duncan initially ask Sam if she's from). I don't think it matters.
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[*]What about Sam's necklace? David thought it was his mother's, but what is the real story?
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I thought it was his mother's, and Sam did buy it at a flea market -- a coincidence that shows that the two of them are cosmically connected and destined to meet.
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[*]Does Helena use drugs or doesn't she?
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Don't know, don't think it matters? As someone else has mentioned, I assumed it would come out that she had diabetes, or something like that, but it wasn't addressed.
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[*]Why were the brains of all students 'lit up' during the first two experiments, and only Angela's brain in the second two?
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I thought it was because he switched equipment, the first machine he used wasn't sensitive enough to capture what he was trying to capture? I forget exactly how it's explained but I thought it was related to the different machines.
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[*]Who wrote the word 'IMPOSTOR' on the roll thingy in David's lab?
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Laura's (real) ghost, as a waring to David. Too bad no one was down there to see it.
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[*]From whom was the message 'check the cars, David?'
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Also Laura's ghost.
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[*]Why did Mrs. Duncan have a key to David's private lab? David says he lets no one in there, not even her.
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I assumed it's because she has access to the whole house, but doesn't go into the room because she's been instructed not to.
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[*]Where did the key to the tower come from?
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The whole tower bit confused me a bit. Maybe Angela had found it at some point, and had been using the tower to spy on David, and she dropped the key?
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[*]And the million dollar question: Did Angela kill Laura?
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Yes, but not intentionally. She was jealous of Laura and angry at being turned away by Dr. Styles during office hours and when her anger flared up, it created a fireball thingie that she couldn't control (which is why the gas petal was melted to the floor). So she caused the accident but didn't mean to (and, I think, didn't even know it).
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[*]Why wasn't the driver of the other car hurt in David and Laura's accident?
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Because the fire was concentrated on David/Laura? An indication that Laura's death wasn't due to the accident itself, but to what happened in the car prior to and during the accident?