Hmm, interesting thread.
The Dark Eye
Hell Cab
Gabriel Knight 2 - First and only FMV game I've ever played.
The Dig
Harvest Moon
Carmaggedon -
I think this was the only game that I've been banned from playing by my parents.
Grim fandango
Outcast
Zelda: Ocarina of time
Syberia
Indigo profecy
Ohh, there are so many... like UPtimist said, I'll have to update this later.