Alan Wake, if it comes out in 2007, but I'm pretty sure it won't.
Other games on the top of my very thin list:
Phantom Hourglass
Phoenix Wright: Trials and Tribulations
Super Mario Galaxy (If I ever get a Nintendo Wii, that is...)
and also since we are Adventure Gamers, I have to say that A Vampyre story is looking hot, and hopefully it wil arrive on time for Christmas.