Update: Apparently, there are currently 3 D&D games in development:
Dungeons&Dragons Online: Stormreach (
http://www.ddo.com)
Dragonshard (
http://www.atari.com/dragonshard)
Neverwinter Nights 2 (
http://www.neverwinternights2.com)
NWN 2 is being developed by Obsidian, so with people like Chris Avellone working on it there should also be a great deal of storytelling involved in the boxed campaign.
edit: (NWN question) Does anybody know if it's possible to have these nice skyboxes
in the game without having HOTU installed?